Pan Fried Cajun Tilapia

If you were to ask me what my favorite food was, I would simply respond…


I love food that screams with flavor, and gives you a good kick in the mouth.

Unfortunately for me, my kids don’t always share the same feelings. So the other day I took advantage of the fact that everyone except me was sick with that yucky stomach bug and I whipped up a tasty tilapia dish just for moi!

Pan Fried Cajun Tilapia displayed on a plate













Oh yes, this Pan Fried Cajun Tilapia is one kick-in-the-mouth fish!

I love cooking with Tilapia. It’s very mild in flavor, {no fishy taste here!} and extremely versatile! I have done just about everything you can do with Tilapia, fried, baked, roasted, grilled, and even microwaved the little guy.

It always turns out tasty!

A hand holding a bottle of Louisiana Hot Sauce in front of a couple pieces of raw Tilapia on a cutting board
















If you are looking for a spicy kick to your Tilapia {or any white fish} then you should try this out. It’s wont disappoint.


Sprinkle the fillet with your favorite hot sauce. I used Louisiana’s but I really love Red Devil {but I ran out of it}. Then just use a pastry or grilling brush and spread it all over.

A hand holding a bottle of Louisiana Cajun Seasoning in front of a couple pieces of raw Tilapia













Grab some good ‘ol Cajun Seasoning and shake, shake, shake!

Coat both sides in yellow cornmeal.

A close up of a seasoned raw Tilapia in a bread of cornmeal
A close up of Tilapia frying on a pan













Toss the fish into a hot skillet with a couple tablespoons of oil. Cook on for 3-4 minutes on both sides or until the fish is no longer transparent and flakes easily.

So easy huh!?

I love how you can whip this up for a quick lunch even!

A close up of Pan Fried Cajun Tilapia topped with sour cream and chives













That sauce on top is just some sour cream and hot sauce whisked together. It gives it a little cooling off effect, but still a good kick.

What’s your favorite way to prepare Tilapia?

A close up of Pan Fried Cajun Tilapia with a piece removed to show off the inside, topped with sour cream and chives
Pan Fried Cajun Tilapia displayed on a plate
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Pan Fried Cajun Tilapia

Tilapia with a little spice to keep things exciting.
Prep Time10 mins
Cook Time10 mins
Total Time20 mins
Course: Dinner
Cuisine: American
Servings: 4
Calories: 430 kcal
Author: Shawn


  • 4 Tilapia fillets
  • Louisiana Hot Sauce, or your favorite if you prefer
  • Cajun Seasoning
  • 1 cup corn meal
  • 2-3 tbsp vegetable oil

For the sauce:

  • 1/2 cup sour cream
  • 2 tbsp Hot Sauce


  • Rinse and pat dry the Tilapia fillets. Brush on and evenly coat each fillet with hot sauce. Sprinkle both sides of fish with Cajun seasoning. Place corn meal in a flat dish. Coat both sides of the fish in the corn meal. Heat the oil in a large skillet over medium high heat. Cook Tilapia in the hot oil for 3-4 minutes per side or until no longer transparent and the fish flakes easily.

For the sauce:

  • Whisk together the sour cream and hot sauce until smooth and combined. Serve on top or on the side of the Cajun Tilapia.
  • Enjoy


Calories: 430kcal | Carbohydrates: 30g | Protein: 39g | Fat: 18g | Saturated Fat: 10g | Cholesterol: 100mg | Sodium: 285mg | Potassium: 691mg | Fiber: 4g | Sugar: 2g | Vitamin A: 179IU | Vitamin C: 5mg | Calcium: 49mg | Iron: 2mg
Keywords: hot sauce, pan fried, Spicy, tilapia
DID YOU MAKE THIS RECIPE?don't forget to share a picture and mention @iwashyoudry on Instagram or tag #iwashyoudry!
About the author

Shawn is the Owner and Creator of I Wash You Dry. She loves to create and share simple, family-friendly recipes. Mom to 5 adorable children and dwells in the desert of Southern Utah.

Shawn Syphus smiling

Shawn Syphus

Hi, I’m Shawn and I’m a busy mom of five; pretending to live on a budget. I love to cook, and explore new recipes, but they have to be quick and easy with as few dishes as possible.

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